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tissue specimens human breast epithelial cell line mcf 10a  (ATCC)
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ATCC tissue specimens human breast epithelial cell line mcf 10a
Tissue Specimens Human Breast Epithelial Cell Line Mcf 10a, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human breast tissue microarray  (Isu Abxis)
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Isu Abxis human breast tissue microarray
Overexpression of DNPH1 in human breast tumors (A) DNPH1 mRNA expression in various breast cancer subtypes was analyzed in published <t>microarray</t> data. Mean with standard deviation and statistical significance compared to normal breast tissue are indicated; ∗∗∗∗, p < 0.0001 (one-way ANOVA, Tukey’s multiple comparisons test). (B) High (top quartile) DNPH1 mRNA levels predict reduced survival. Data derived from published microarray experiments ; p < 0.0001 (log rank test). (C) DNPH1 protein expression in human breast cell lines assayed by Western blotting. (D) Examples of immunohistochemical staining with DNPH1 antibodies on matching normal and cancerous breast tissue. Scale bars, 0.1 mm. (E) DNPH1 protein expression was measured by immunohistochemistry in 20 matching normal and cancerous human breast tissues; two-tailed, paired t test.
Human Breast Tissue Microarray, supplied by Isu Abxis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human breast tissue  (Human Protein Atlas)
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Human Protein Atlas human breast tissue
Overexpression of DNPH1 in human breast tumors (A) DNPH1 mRNA expression in various breast cancer subtypes was analyzed in published <t>microarray</t> data. Mean with standard deviation and statistical significance compared to normal breast tissue are indicated; ∗∗∗∗, p < 0.0001 (one-way ANOVA, Tukey’s multiple comparisons test). (B) High (top quartile) DNPH1 mRNA levels predict reduced survival. Data derived from published microarray experiments ; p < 0.0001 (log rank test). (C) DNPH1 protein expression in human breast cell lines assayed by Western blotting. (D) Examples of immunohistochemical staining with DNPH1 antibodies on matching normal and cancerous breast tissue. Scale bars, 0.1 mm. (E) DNPH1 protein expression was measured by immunohistochemistry in 20 matching normal and cancerous human breast tissues; two-tailed, paired t test.
Human Breast Tissue, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human breast cancer tissue  (Anhui Medical University)
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Anhui Medical University human breast cancer tissue
ARTS is predominantly expressed in resistant <t>breast</t> <t>cancer</t> <t>tissues</t> and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.
Human Breast Cancer Tissue, supplied by Anhui Medical University, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human breast cancer tissue array  (Novus Biologicals)
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Novus Biologicals human breast cancer tissue array
ARTS is predominantly expressed in resistant <t>breast</t> <t>cancer</t> <t>tissues</t> and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.
Human Breast Cancer Tissue Array, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human breast tumor tissue arrays  (Servicebio Inc)
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Servicebio Inc human breast tumor tissue arrays
ARTS is predominantly expressed in resistant <t>breast</t> <t>cancer</t> <t>tissues</t> and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.
Human Breast Tumor Tissue Arrays, supplied by Servicebio Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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normal human breast tissue lysate  (Novus Biologicals)
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Novus Biologicals normal human breast tissue lysate
ARTS is predominantly expressed in resistant <t>breast</t> <t>cancer</t> <t>tissues</t> and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.
Normal Human Breast Tissue Lysate, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human breast tissue device trade name  (Abbott Laboratories)
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Abbott Laboratories human breast tissue device trade name
ARTS is predominantly expressed in resistant <t>breast</t> <t>cancer</t> <t>tissues</t> and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.
Human Breast Tissue Device Trade Name, supplied by Abbott Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Overexpression of DNPH1 in human breast tumors (A) DNPH1 mRNA expression in various breast cancer subtypes was analyzed in published microarray data. Mean with standard deviation and statistical significance compared to normal breast tissue are indicated; ∗∗∗∗, p < 0.0001 (one-way ANOVA, Tukey’s multiple comparisons test). (B) High (top quartile) DNPH1 mRNA levels predict reduced survival. Data derived from published microarray experiments ; p < 0.0001 (log rank test). (C) DNPH1 protein expression in human breast cell lines assayed by Western blotting. (D) Examples of immunohistochemical staining with DNPH1 antibodies on matching normal and cancerous breast tissue. Scale bars, 0.1 mm. (E) DNPH1 protein expression was measured by immunohistochemistry in 20 matching normal and cancerous human breast tissues; two-tailed, paired t test.

Journal: iScience

Article Title: Promotion of breast cancer by the DNPH1 enzyme

doi: 10.1016/j.isci.2026.115227

Figure Lengend Snippet: Overexpression of DNPH1 in human breast tumors (A) DNPH1 mRNA expression in various breast cancer subtypes was analyzed in published microarray data. Mean with standard deviation and statistical significance compared to normal breast tissue are indicated; ∗∗∗∗, p < 0.0001 (one-way ANOVA, Tukey’s multiple comparisons test). (B) High (top quartile) DNPH1 mRNA levels predict reduced survival. Data derived from published microarray experiments ; p < 0.0001 (log rank test). (C) DNPH1 protein expression in human breast cell lines assayed by Western blotting. (D) Examples of immunohistochemical staining with DNPH1 antibodies on matching normal and cancerous breast tissue. Scale bars, 0.1 mm. (E) DNPH1 protein expression was measured by immunohistochemistry in 20 matching normal and cancerous human breast tissues; two-tailed, paired t test.

Article Snippet: Human breast tissue microarray , ISU Abxis , A312.

Techniques: Over Expression, Expressing, Microarray, Standard Deviation, Derivative Assay, Western Blot, Immunohistochemical staining, Staining, Immunohistochemistry, Two Tailed Test

ARTS is predominantly expressed in resistant breast cancer tissues and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.

Journal: Research

Article Title: ARTS Confers Chemoresistance of Breast Cancer by Inducing Apoptosis-Dependent Autophagy via Livin–MDM2–p53 Pathway

doi: 10.34133/research.1086

Figure Lengend Snippet: ARTS is predominantly expressed in resistant breast cancer tissues and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.

Article Snippet: Human breast cancer tissue samples were obtained from the First Affiliated Hospital of Anhui Medical University (Hefei, Anhui, China).

Techniques: